Cialis (Tadalafil)

What Is Cialis?


Cialis is a brand name for a substance with the generic name tadalafil. It is used to treat men who experience difficulty having and maintaining an erect penis for satisfactory sexual performance.

Cialis was approved by the American Food And Drug Administration on November 21, 2003. It was first marketed by Lilly ICOS LLC, a joint venture between Eli Lilly and ICOS Corporation.

Cialis produces results similar to viagra, but the effects of cialis last longer than viagra. The most common cialis dose size is 20 milligrams, but some men find 10 milligrams is enough.

Cialis is effective for about 90% of men with psychological impotence caused by things like stress, fatigue, anxiety, depression. It is effective in 70%-80% of cases when used to treat erectile dysfunction caused by physical factors.


How Long Do The Effects Of Cialis Last

The effects of cialis have been shown to last 24-36 hours in a majority of users. The effects of viagra have been shown to last 4-6 hours in a majority of users.

Some men like the fact that cialis works for up to 36 hours and allows the user and his partner to relax, forget about planning intimacy and let things happen when the moment is right.

24-36 hours might seem ideal but some men report they switched back to viagra because 6 hours or less was what they preferred.

Taking cialis does not increase sexual desire and it will not give you an erection for 36 hours. Most men who take cialis report that for up to 36 hours after taking cialis, an erection can be sustained when the penis was stimulated by touch.

In most cases, within 36 hours of taking 20 milligrams of cialis or generic cialis, you will be able to get and maintain an erection to orgasm.

After orgasm, the penis will return to its pre-aroused state. Some men with erectile dysfunction may be able to have one or more orgasms after the first.


How Does Cialis Work

Medications like cialis, viagra, and levitra work by inhibiting a chemical called phosphodiesterase type 5. Because of their mode of action, these drugs are commonly referred to simply as PDE5 inhibitors.

When a man gets sexually excited, it triggers cells in the penis to produce nitric oxide. The increase in nitric oxide will in turn cause production of cyclic guanosine monophosphate (cGMP).

The cGMP causes arteries in part of the penis to relax and allow more blood to flow through them. The increase in blood flow causes an erection.

If the enzyme phosphodiesterase type 5 (PDE5) is of sufficient quantity, it will attack the cGMP and erection will not be maintained.

Cialis and other PDE5 inhibitors reduce the amount of PDE5 available to attack cGMP. With a reduction of PDE5, most men are able to maintain an erection to orgasm.