Dopamine And Serotonin Precursors

Dopamine And Serotonin Precursors, Amino Acids


There is an important relationship between dopamine precursors, serotonin precursors, amino acids. Taking large amounts of one, may unbalance the levels of others.

This information is most applicable to those who take one of these substances on a daily basis for medical reasons, to supplement because their diet lacks them, or for other reasons.

If you take one of these substances occasionally there is probably not going to be a problem. However, if you are taking them on a regular basis, especially in large doses, it is in your best interest to balance things out.

Dopamine Precursors
Serotonin Precursors
Sulfur Amino Acids
Notes
Links


Dopamine Precursors

Dopamine is a chemical that has a significant effect on the body and brain. One of the important roles it plays is that of neurotransmitter. The chemicals phenylalanine, tyrosine, L-dopa are classified as dopamine precursors.

In the body:
--- Phenylalanine is converted to Tyrosine.
--- Tyrosine is converted to L-dopa.
--- L-dopa is converted to Dopamine.

Various individuals who have the need to increase levels of these chemicals sometimes take phenylalanine, tyrosine, or L-dopa as medicine, dietary supplement, or for some other reason.

Phenylalanine is classified as an essential amino acid. It can not be synthesized by the body and must be obtained from diet or by taking phenylalanine supplements.

Large doses of phenylalanine:
--- May reduce serotonin levels.
--- May reduce aromatic amino acid levels.
--- Aromatic amino acids: tyrosine, L-dopa, tryptophan, 5-HTP.

If you take phenylalanine, a small dose of tyrosine, L-dopa, tryptophan, 5-HTP can help keep serotonin and aromatic amino acid levels within proper ranges.

Tyrosine is classified as a non-essential amino acid. It can normally be synthesized from phenylalanine but for certain individuals, notably those with phenylketonuria, their body may not be able to.

Large doses of tyrosine:
--- May reduce 5-HTP levels.
--- May reduce serotonin levels.
--- May reduce sulfur amino acid levels.
--- Sulfur amino acids include: cysteine and methionine.

If you take a tyrosine, a small dose of 5-HTP can help keep 5-HTP and serotonin levels within proper ranges. A small dose of cysteine and methionine can help keep sulfur amino acid levels within proper ranges.

L-dopa is converted to the neurotransmitter dopamine. Dopamine is then converted to norepinephrine, and norepinephrine (noradrenalin) is converted to epinephrine (adrenalin).

Large doses of L-dopa:
--- May reduce tryptophan levels.
--- May reduce serotonin levels.
--- May reduce tyrosine levels.
--- May reduce sulfur amino acid levels.
--- Sulfur amino acids include: cysteine and methionine.

If you take L-dopa, a small dose of tryptophan and 5-HTP can help maintain tryptophan and serotonin levels. A small dose of tyrosine can help maintain tyrosine levels. A small dose of cysteine and methionine can help maintain sulfur amino acid levels.


Serotonin Precursors

Serotonin is another chemical that has multiple important functions in the body and brain. One of these important functions is acting as a neurotransmitter. The chemicals tryptophan and 5-HTP are classified as serotonin precursors.

In the body:
--- Tryptophan is converted to 5-HTP.
--- 5-HTP is then converted to Serotonin.

Various individuals who have the need to increase levels of these chemicals sometimes take tryptophan or 5-HTP as medicine, dietary supplements, or for other reasons.

Large doses of tryptophan may reduce dopamine levels.
Large doses of 5-HTP may reduce dopamine levels.

If you take a large dose of L-tryptophan, a small dose of L-dopa taken at the same time can help keep dopamine levels within proper ranges.

If you take a large dose of 5-HTP, a small dose of L-dopa taken at the same time can help keep dopamine levels within proper ranges.


Sulfur Amino Acids

Sulfur amino acids include cysteine and methionine. Cysteine and methionine perform many important functions in the body and are required to make proteins, as well as performing other duties.

--- Sulfur amino acids may reduce dopamine levels.
--- Sulfur amino acids may reduce serotonin levels.

If you take a large dose of one or more sulfur amino acids, a small dose of L-dopa taken at the same time can help keep dopamine levels within proper ranges and a small dose of 5-HTP can help keep serotonin levels within proper ranges.


Notes

By taking a small dose of a substance that may be reduced by taking another substance, you can balance things out. If you do not, there is a greater chance of having problems.

For instance, 5-HTP can reduce levels of dopamine. By not taking a small dose of L-dopa with 5-HTP, there is more of a chance of experiencing symptoms related to low dopamine levels.

For a more detailed explanation of the relationship between dopamine and serotonin precursor supplements, see the National Center for Biotechnology Information web page about 5-HTP efficacy and contraindications. that is located here.


Links

Phenylalanine.
Tyrosine.
L-dopa.
Tryptophan.
5-HTP.
Cysteine.
Methionine.
Dopamine.
Serotonin.
Neurotransmitters.
Essential amino acids.
Non-Essential amino acids.