Phenibut, also spelled fenibut or phenybut, is a generic name for a compound that has been marketed as a drug under brand names that include Citrocard and Noofen.
Phenibut was first synthesized by Professor Vsevolod Perekalin and his research team in the 1960s, at the A. I. Herzen Leningrad Pedagogical Institute in the Soviet Union. Testing was preformed at the Institute of Experimental Medicine, USSR Academy of Medical Sciences.
In Eastern Europe, phenybut has been utilized to treat various conditions including: alcoholism, anxiety, asthenia, depression, insomnia, post traumatic stress disorder, stuttering, vestibular disorders, other medical problems.
Phenibut can be classified in various drug categories including:
--- Anticonvulsant - inhibits or eliminates convulsions.
--- Anxiolytic - can reduce or eliminate anxiety.
--- Depressant - slows the cns, induces relaxation or sleepiness.
--- GABA receptor agonist - binds to GABA receptors.
--- Hypnotic/Sedative - can induce or improve sleep.
--- Nootropic - can improve mental functions.
--- Psychotropic - can alter mood. perception, or consciousness.
Phenibut has been successfully employed as a:
--- Treatment for symptoms of agoraphobia.
--- Treatment for symptoms of anxiety.
--- Treatment for symptoms of bipolar disorder.
--- Treatment for symptoms of depression.
--- Treatment for symptoms of osteoarthritis.
--- Treatment for symptoms of panic attacks.
--- Treatment for symptoms of PTSD.
--- Treatment for symptoms of social phobia.
--- Reduce fear.
--- Induce sleep.
--- Reduce pain.
--- Relax muscles.
--- Reduce anxiety.
--- Help you mentally slow down and focus.
--- Help ease symptoms of opioid withdrawal.
--- Possibly increase libido (freudian and jungian).
--- Act as mental stabilizer for various mental disorders.
Phenibut can take several hours to work, so it might require planning to time things correctly if you are taking it to cope with an anxious, or similar, situation. Phenibut may increase the potency of antipsychotic, opioid, or tranquilizer medications.
Phenibut can reduce stress without negatively affecting mental or physical performance. Allowing you to stay mentally focused, unlike benzodiazepines and other tranquilizers. However, for some it can be both mentally and physically sedating.
Audiophiles may find music sounds better.
--- Introverts may feel like talking and socializing.
--- Can replace opioid pain medication for mild to moderate pain.
--- May be preferable to benzodiazepines and other anti-anxiety drugs.
--- Similar in effect to alcohol or benzos with less mental impairment.
Doses as low as 25-50 milligrams are satisfactory to a minority of consumers. A majority require 250-750 mg, sometimes higher. Phenibut powder can be put into a capsule or mixed with liquid, like orange juice to mask the taste, and drank.
Unless instructed to by your physician or health care provider, it would be best to limit doses sizes to a maximum of 750 milligrams and daily intake to under 1500 milligrams. Effects of large doses can last up to 48 hours.
For anxiety (including social anxiety) positive results are often obtained from 250-500 milligrams taken 1-3 times daily, on days when it's required. Some sufferers prefer larger doses, in the range of 2-3 grams (2000-3000 milligrams) or more, once a week.
Some people find phenibut more stimulating at larger dose sizes, while doses under 500 mg induce sleep. Most say it always affects them like depressant, some say it always affects them like a stimulant, regardless of if it is taken in small or large doses.
Addiction, tolerance, withdrawal have been observed in people who take phenibut on a frequent basis. The best way to avoid this is to limit intake to 1-2 times a week (3-4 days between doses) or less often.
Phenibut is water soluble, can be mixed with liquids and drank or put in a capsule. It works quickest when taken on an empty stomach. Doses too large for your body to handle produce mental and physical impaired, reduce the dose size next time.
You will have to experiment with the dosage, preferably starting with small 100-150 mg doses and working your way up, to optimal levels. Bear in mind the possibility of it acting as a depressant in small doses, and stimulant at larger dose levels.
It takes about 20 minutes or longer to start working and 2 hours to work fully. It can take up to 3-4 hours to work fully, and for some individuals up to 6 hours or more.
The strongest effect can be felt for about 5-8 hours after it has begun to work fully, peak effects of large doses can last all day. Some lesser lingering sensations can be felt for up to 48 hours.
When combined with substances that have stimulant properties, phenibut can reduce or eliminate the jitters that those who are stimulant sensitive mat feel after ingesting substances with stimulating properties.
Phenibut can be utilized by itself or in combination with kratom to increase analgesic properties of both medications, or to ease the symptoms associated with opioid withdrawal.
Prior to utilizing phenibut, to be safe discuss it with your physician. On your first attempt it might be the best thing to try working with a small quantity, somewhere in the neighborhood of 100-150 milligrams or less.
A small dose size will give you an indication of the possible results as well as alerting you to any negative reactions. At small dose sizes, the effects are subtle and some people might not notice anything. You can increase the dose size on subsequent attempts.
In some cases, phenibut intake will cause a hung-over feeling the next day after taking it. In other cases when waking up after taking it the previous day, there are reports of a continuation of the positive effects and an overall positive mood.
Drinking alcohol products while taking phenibut may cause negative results. Also, when combined with alcohol it can make hangovers feel even worse. Do not combine with anticonvulsants, epilepsy medications, MAOIs, or sedatives.
Ingesting it frequently and dose sizes over 250-500 milligrams may cause more problems with addiction, tolerance, withdrawal. Large dose have more of a chance of causing things like dizziness headaches, nausea. Very large doses may produce hallucinations.
Addiction and tolerance can develop quickly depending on body chemistry and mental disposition. Phenibut withdrawal can be severe and is sometimes compared with benzodiazepine withdrawal, but doesn't last as long.
Withdrawal lasts several weeks, symptoms include: dizziness, fast heartbeat, hallucinations, insomnia, irritability, low energy, mental agitation, nausea, nervousness, no appetite, psychosis, severe anxiety, tension, tremors, vomiting.
For someone who has been taking it on a daily basis, reducing the dose size gradually and tapering off, rather than completely stopping intake in one shot is recommended. This is to limit the severity of withdrawal effects.